Anti-Mouse CD140a (PDGF Receptor a) APC
The APA5 monoclonal antibody specifically binds to the mouse CD140a molecule, otherwise known as the Platelet-Derived Growth Factor (PDGF) Receptor alpha chain. CD140a is a receptor tyrosine kinase expressed on embryonic tissues and adult mesenchymal-derived cells. It binds to PDGF A and B chains and is reported to be involved with wound healing and exhibits chemo-attractant properties. The APA5 antibody blocks the binding of PDGF-AA to the PDGF receptor. Reparixin (L-lysine salt)
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Clone
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APA5
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Format: |
APC
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Applications
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FC
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Reactivity
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Mouse
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Isotype:
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Rat IgG2a, kappa
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted biotin was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Fruttiger, M., Calver, A. R., Krüger, W. H., Mudhar, H. S., Michalovich, D., Takakura, N., … & Richardson, W. D. (1996). PDGF mediates a neuron–astrocyte interaction in the developing retina. Neuron, 17(6), 1117-1131. Takakura, N., Yoshida, H., Ogura, Y., Kataoka, H., Nishikawa, S., & Nishikawa, S. I. (1997). PDGFRα expression during mouse embryogenesis: immunolocalization analyzed by whole-mount immunohistostaining using the monoclonal anti-mouse PDGFRα antibody APA5. Journal of Histochemistry & Cytochemistry, 45(6), 883-893. Takakura, N., Yoshida, H., Kunisada, T., Nishikawa, S., & Nishikawa, S. I. (1996). Involvement of Platelet-Derived Growth Factor Receptor-&agr; in Hair Canal Formation. Journal of investigative dermatology, 107(5), 770-777. |