Anti-Mouse CD105 (Endoglin) PE
The MJ7/18 monoclonal antibody specifically reacts with mouse CD105 (Endoglin), a 90kDA homodimeric glycoprotein expressed on vascular endothelial cells. CD105 is a marker for tumor angiogenesis research by identifying proliferating endothelium. It is also suggested to be involved in embryonic angiogenesis and cellular adhesion. IPI551
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Clone
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MJ7/18
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Format: |
PE
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Applications
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FC
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Reactivity
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Mouse
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Isotype:
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Rat IgG2a, kappa
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Ge, A. Z., & Butcher, E. C. (1994). Cloning and expression of a cDNA encoding mouse endoglin, an endothelial cell TGF-β ligand. Gene, 138(1), 201-206. Onoe, T., Ohdan, H., Tokita, D., Shishida, M., Tanaka, Y., Hara, H., … & Asahara, T. (2005). Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice. The Journal of Immunology, 175(1), 139-146. St-Jacques, S., Cymerman, U. R. S. Z. U. L. A., Pece, N. A. D. I. A., & Letarte, M. (1994). Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells. Endocrinology, 134(6), 2645-2657. |