Anti-Human IL-4 SAFIRE Purified
The MP4-25D2 monoclonal antibody specifically reacts with human Interleukin-4 (IL-4), expressed by the activated T cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen. The MP4-25D2 is a neutralizing antibody and is reported to be cross-reactive with rhesus monkeys. Clozapine (N-oxide)
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Clone
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MP4-25D2
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Format: |
SAFIRE Purified
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Applications
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FA, Neutralization
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Reactivity
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Human
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Isotype:
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Rat IgG1, kappa
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| Research Interest: | , , Cytokines & Growth Factors |
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Preperation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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Abrams, J. S., Roncarolo, M. G., Yssel, H., Andersson, U., Gleich, G. J., & Silver, J. E. (1992). Strategies of anti‐cytokine monoclonal antibody development: immunoassay of IL‐10 and IL‐5 in clinical samples.Immunological reviews, 127(1), 5-24. Chrétien, I., Van Kimmenade, A., Pearce, M. K., Banchereau, J., & Abrams, J. S. (1989). Development of polyclonal and monoclonal antibodies for immunoassay and neutralization of human interleukin-4. Journal of immunological methods, 117(1), 67-81. Jung, T., Schauer, U., Rieger, C., Wagner, K., Einsle, K., Neumann, C., & Heusser, C. (1995). Interleukin‐4 and interleukin‐5 are rarely co‐expressed by human T cells. European journal of immunology, 25(8), 2413-2416. |