Anti-Human IL-4 PE
The 8D4-8 monoclonal antibody specifically reacts with human IL-4, expressed by the activated T cells and mast cells. IL-4 is species-specific and stimulates the proliferation and differentiation of B lymphocytes. It upregulates the expression of IgE receptors and class II MHC antigen. The 8D4-8 antibody neutralizes the IL-4 cytokine. LDN193190
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Clone
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8D4-8
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Format: |
PE
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Applications
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FC
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Reactivity
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Human
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Isotype:
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Mouse IgG1, kappa
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| Research Interest: | , , Cytokines & Growth Factors |
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Bird, C., Wadhwa, M., & Thorpe, R. (1991). Development of immunoassays for human interleukin 3 and interleukin 4, some of which discriminate between different recombinant DNA-derived molecules. Cytokine, 3(6), 562-567. Prussin, C., & Metcalfe, D. D. (1995). Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies. Journal of immunological methods, 188(1), 117-128. Kon, O. M., Sihra, B. S., Till, S. J., Corrigan, C. J., Kay, A. B., & Grant, J. A. (1998). Unstimulated basophils in atopic and nonatopic subjects express intracellular interleukin‐4: detection by flow cytometry. Allergy, 53(9), 891-896. |