Anti-Human Foxp1 Purified
The JC12 monoclonal antibody specifically reacts with human Foxp1, a winged helix transcription factor that is expressed in almost all human tissue. In several tumor types, the gene is lost suggesting it plays a tumor suppressive role. It plays an important role in the development of the brain, lungs, thymus, and heart. Foxp1 is also involved in the development of early B cells. Exendin-4
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Clone
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JC12
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Format: |
Purified
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Applications
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FC, IHC, WB,
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Reactivity
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Human
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Isotype:
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Mouse IgG2a, kappa
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Banham, A. H., Beasley, N., Campo, E., Fernandez, P. L., Fidler, C., Gatter, K., … & Cordell, J. L. (2001). The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p. Cancer research,61(24), 8820-8829. Banham, A. H., Connors, J. M., Brown, P. J., Cordell, J. L., Ott, G., Sreenivasan, G., … & Gascoyne, R. D. (2005). Expression of the FOXP1 transcription factor is strongly associated with inferior survival in patients with diffuse large B-cell lymphoma. Clinical Cancer Research, 11(3), 1065-1072. Arber, S. (2008). FoxP1: conducting the Hox symphony in spinal motor neurons. Nature neuroscience, 11(10), 1122-1124. |