Anti-Human CD66b Purified
The G10F5 monoclonal antibody specifically reacts with human CD66b, a 100kDa glycosylphosphatidylinositol (GPI) linked protein in the granulocyte-specific activation family. CD66b is expressed on granulocytes, neutrophils, and eosinophils. It is reported that this molecule plays a role in regulating neutrophil activation and cellular adhesion. It was previously classified as CD67, but renamed CD66b in the Fifth HLDA Workshop. ABT-201
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Clone
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G10F5
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Format: |
Purified
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Applications
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FC, IHC
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Reactivity
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Human
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Isotype:
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Mouse IgM, kappa
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Preperation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. Lund-Johansen, F. R. I. D. T. J. O. F., Olweus, J. O. H. A. N. N. A., Horejsi, V. A. C. L. A. V., Skubitz, K. M., Thompson, J. S., Vilella, R., & Symington, F. W. (1992). Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65). The Journal of Immunology, 148(10), 3221-3229. Schmidt, T., Zündorf, J., Grüger, T., Brandenburg, K., Reiners, A. L., Zinserling, J., & Schnitzler, N. (2012). CD66b overexpression and homotypic aggregation of human peripheral blood neutrophils after activation by a gram-positive stimulus. Journal of leukocyte biology, 91(5), 791-802. |