Anti-Human CD48 SAFIRE Purified
The 156-4H9 monoclonal antibody specifically reacts with human CD48, a GPI-linked glycoprotein in the Ig superfamily. CD48 was previously known as BCM1 in mice, Blast-1 in humans, and OX-45 in rats. Its ligands are CD2 and CD244 and it is expressed on leukocytes to the exclusion of non-hematopoietic cells and its expression increases in B cells upon activation. EMD638683
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Clone
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156-4H9
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Format: |
SAFIRE Purified
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Applications
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FC, FA
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Reactivity
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Human
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Isotype:
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Mouse IgG1
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Preperation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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González-Álvaro, I., Domínguez-Jiménez, C., Ortiz, A. M., Núñez-González, V., Roda-Navarro, P., Fernández-Ruiz, E., … & Sánchez-Madrid, F. (2006). Interleukin-15 and interferon-γ participate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production. Arthritis research & therapy, 8(4), R88. Katagiri, T., Qi, Z., Ohtake, S., & Nakao, S. (2011). GPI‐anchored protein‐deficient T cells in patients with aplastic anemia and low‐risk myelodysplastic syndrome: implications for the immunopathophysiology of bone marrow failure.European journal of haematology, 86(3), 226-236. Yokoyama, S., Staunton, D., Fisher, R., Amiot, M., Fortin, J. J., & Thorley-Lawson, D. A. (1991). Expression of the Blast-1 activation/adhesion molecule and its identification as CD48. The Journal of immunology, 146(7), 2192-2200. |