Anti-Human CD42b Purified
The HIP1 monoclonal antibody specifically binds to human CD42b, a 145kDa transmembrane protein known as the platelet glycoprotein Ib alpha chain (gpIbα). CD42 is expressed on platelets and megakaryocytes and is reported to be involved in platelet adhesion. The HIP1 antibody inhibits collage-induced aggregation and platelet to von Willebrand Factor (vWF) binding. NVP-BKM120
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Clone
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HIP1
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Format: |
Purified
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Applications
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FC, FA, IHC, WB
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Reactivity
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Human
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Isotype:
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Mouse IgG1, kappa
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Preperation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Gohda, F., Uchiumi, H., Handa, H., Matsushima, T., Tsukamoto, N., Morita, K., … & Karasawa, M. (2007). Identification of inherited macrothrombocytopenias based on mean platelet volume among patients diagnosed with idiopathic thrombocytopenia. Thrombosis research, 119(6), 741-746. George, N. P. E., Wei, Q., Shin, P. K., Konstantopoulos, K., & Ross, J. M. (2006). Staphylococcus aureus adhesion via Spa, ClfA, and SdrCDE to immobilized platelets demonstrates shear-dependent behavior. Arteriosclerosis, thrombosis, and vascular biology, 26(10), 2394-2400. Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. |