Anti-Human CD38 PE
The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, macrophages, dendritic cells, and thymocytes. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31. Pexidartinib
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Clone
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HIT2
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Format: |
PE
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Applications
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FC
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Reactivity
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Human
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Isotype:
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Mouse IgG1, kappa
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Deaglio, S., Morra, M., Mallone, R., Ausiello, C. M., Prager, E., Garbarino, G., … & Malavasi, F. (1998). Human CD38 (ADP-ribosyl cyclase) is a counter-receptor of CD31, an Ig superfamily member. The Journal of Immunology,160(1), 395-402. McMichael, A. J. (1987). Leucocyte typing III: white cell differentiation antigens. Oxford University Press, USA. HORENSTEIN, A., STOCKINGER, H., Imhof, B., & MALAVASI, F. (1998). CD38 binding to human myeloid cells is mediated by mouse and human CD31.Biochem. J, 330, 1129-1135. |