Anti-Human CD31 (PECAM-1) Purified
The WM59 monoclonal antibody specifically reacts with human CD31, a 130-140 kDA type I transmembrane glycoprotein also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. CD31 is reported to bind to CD38 and is expressed on platelets, monocytes, granulocytes, and endothelial cells. It plays a role in angiogenesis, wound healing, cellular migration, and signal transduction. CC-930
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Clone
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WM59
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Format: |
Purified
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Applications
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FC, IHC
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Reactivity
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Human
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Isotype:
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Mouse IgG1, kappa
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| Cell Type: | , , , |
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Schlossman, S. F. (1995). Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press. Porat, Y., Porozov, S., Belkin, D., Shimoni, D., Fisher, Y., Belleli, A., … & Savion, N. (2006). Isolation of an adult blood‐derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.British journal of haematology, 135(5), 703-714. Vaporciyan, A. A., DeLisser, H. M., Yan, H. C., Jones, M. L., Ward, P. A., & Albelda, S. M. (1993). Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo. Science, 262(5139), 1580-1582. |