Anti-Human CD27 APC
The O323 monoclonal antibody specifically binds to the human CD27, which is a lymphocyte-specific member of the TNF/NGF-R family, expressed on a subset of human thymocytes and the majority of the mature T cells. CD27 is upregulated by T lymphocytes stimulation, and binds to CD70, enhancing the interaction between T and B lymphocytes.
CD27 is a memory marker of B cells.
Clone
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O323
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Format: |
APC
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Applications
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FC
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Reactivity
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Human
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Isotype:
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Mouse IgG1, kappa
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Research Interest: | , |
Cell Type: | , , |
Protein Cross Reactivity: | Baboon, Cynomolgus, Rhesus |
Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Correia, D. V., Fogli, M., Hudspeth, K., da Silva, M. G., Mavilio, D., & Silva-Santos, B. (2011). Differentiation of human peripheral blood Vδ1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells. Blood, 118(4), 992-1001. |