Anti-Human CD14 SAFIRE Purified
The 61D3 monclonal antibody specifically binds to human CD14, a co-receptor for bacterial lipopolysaccharides (LPS). It is expressed on some dendritic cells, monocytes, and neutrophils. CD14 is involved in the body’s innate immune response and cytokine expression in monocytes and neutrophils. GDC-0810
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Clone
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61D3
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Format: |
SAFIRE Purified
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Applications
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FC, FA
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Reactivity
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Human
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Isotype:
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Mouse IgG1, kappa
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Preperation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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Nunez, G., Ugolini, V., Capra, J. D., & Stastny, P. (1982). Monoclonal Antibodies against Human Monocytes. Scandinavian journal of immunology,16(6), 515-523 Devitt, A., Moffatt, O. D., Raykundalia, C., Capra, J. D., Simmons, D. L., & Gregory, C. D. (1998). Human CD14 mediates recognition and phagocytosis of apoptotic cells. Nature, 392(6675), 505-509. Henriksen, P. A., Devitt, A., Kotelevtsev, Y., & Sallenave, J. M. (2004). Gene delivery of the elastase inhibitor elafin protects macrophages from neutrophil elastase-mediated impairment of apoptotic cell recognition. FEBS letters,574(1), 80-84. |