Anti-Human CD11a SAFIRE Purified
The HI111 monoclonal antibody specifically reacts with human CD11a, a 180kDA glycoprotein. CD11a is the integrin alpha L chain that forms with CD18 the heterodimer molecule Lymphocyte Function-associated Antigen-1 (LFA-1). LFA-1 is expressed on all leukocytes and is involved in intercellular adhesions. The heterodimer can bind to CD50 (ICAM-3), CD54 (ICAM-1), and CD102 (ICAM-2). Emricasan
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Clone
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HI111
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Format: |
SAFIRE Purified
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Applications
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FC, FA
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Reactivity
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Human
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Isotype:
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Mouse IgG1, kappa
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| Research Interest: | |
| Cell Type: | , Th1 cells |
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Preperation:
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The product should be stored undiluted at 4°C. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
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Formulation:
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Phosphate-buffered aqueous solution, ph7.2.
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References:
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Inghirami, G., Wieczorek, R., Zhu, B. Y., Silber, R., Dalla-Favera, R., & Knowles, D. M. (1988). Differential expression of LFA-1 molecules in non-Hodgkins lymphoma and lymphoid leukemia. Blood, 72(4), 1431-1434. Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989. Bochner, B. S., Luscinskas, F. W., Gimbrone, M. A., Newman, W., Sterbinsky, S. A., Derse-Anthony, C. P., … & Schleimer, R. P. (1991). Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules. The Journal of experimental medicine, 173(6), 1553-1557. |