Animal-Free Recombinant Murine FGF-basic
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant murine FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues. Manufactured using all non-animal reagents.
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Source: |
E. Coli
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Purity:
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Above 95% as determined by SDS-PAGE Analysis.
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Cross Reactivity: |
Rabbit
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Biological Activity
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Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.1 ng/ml corresponding to a specific activity of ≥ 1 x 10decorateTable(product-attribute-specs-table) |