Animal-Free Recombinant Human IL-17E


IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NF-κB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains. Manufactured using all non-animal reagents.

T-5226


Source:
E. Coli
&nbsp

Purity:
Above 98% as determined by SDS-PAGE Analysis.
&nbsp

Cross Reactivity:
NULL
&nbsp

Biological Activity
Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10-100ng.
&nbsp

AA Sequence
MYSHWPSCC PSKGQDTSE ELLRWSTVP VPPLEPARP NRHPESCRA SEDGPLNSR AISPWRYEL DRDLNRLPQ DLYHARCLC PHCVSLQTG SHMDPRGNS ELLYHNQTV FYRRPCHGE KGTHKGYCL ERRLYRVSL ACVCVRPRV MG
Research Interest: Inflammation
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
25µg

$215.00

100µg

$660.00

500µg

$1,980.00

1mg

$3,300.00

MED: 19057193

Animal-Free Recombinant Human IL-17E


IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NF-κB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains. Manufactured using all non-animal reagents.

THZ5


Source:
E. Coli
&nbsp

Purity:
Above 98% as determined by SDS-PAGE Analysis.
&nbsp

Cross Reactivity:
NULL
&nbsp

Biological Activity
Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10-100ng.
&nbsp

AA Sequence
MYSHWPSCC PSKGQDTSE ELLRWSTVP VPPLEPARP NRHPESCRA SEDGPLNSR AISPWRYEL DRDLNRLPQ DLYHARCLC PHCVSLQTG SHMDPRGNS ELLYHNQTV FYRRPCHGE KGTHKGYCL ERRLYRVSL ACVCVRPRV MG
Research Interest: Inflammation
Protein Cross Reactivity: NULL

Availability: In stock

Size Price Qty
25µg

$215.00

100µg

$660.00

500µg

$1,980.00

1mg

$3,300.00

MED: 19063664

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