Animal-Free Recombinant Human FGF-10
FGF-10 is a heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-10 is most related to KGF/FGF-7 and is expressed during the development and preferentially in adult lungs. It signals through the FGFR 2b. Recombinant human FGF-10 is a 19.3 kDa protein consisting of 170 amino acid residues. Manufactured using all non-animal reagents.
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Source: |
E. Coli
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Purity:
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Above 95% as determined by SDS-PAGE Analysis.
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Cross Reactivity: |
Chicken, Mouse
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Biological Activity
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The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF- receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
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AA Sequence
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MLGQDMVSP EATNSSSSS FSSPSSAGR HVRSYNHLQ GDVRWRKLF SFTKYFLKI EKNGKVSGT KKENCPYSI LEITSVEIG VVAVKAINS NYYLAMNKK GKLYGSKEF NNDCKLKER IEENGYNTY ASFNWQHNG RQMYVALNG KGAPRRGQK TRRKNTSAH FLPMVVHS
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| Research Interest: | , , Proliferation and Cell Cycle |
| Protein Cross Reactivity: | Chicken, Mouse |